Body systems & senses
I've noted on the Internet that a particular bodybuilding proceedure is to do specific exercises with high resistance weights to the legs to release human growth hormone stores within the legs. If the reports are true, I would like to know how the body stores the growth hormone within the legs as well as how it is released. I am hoping to correlate controlled release of the growth hormone through walking, jogging and sprinting. Thank you for your assistance.
Dear Samuel, Thank you for submitting your question to AskNSDL. As a reference librarian, I can suggest several strategies for locating resources. I'll provide a a few URL's that may be useful to you, but there are many more. Try your own searches and you'll discover a lot of material on this topic! In order to find evidence-based, topical articles specific to your question, I went to PubMed,http://www.ncbi.nlm.nih.gov/entrez/query.fcgi, the National Library of Medicine's,http://www.nlm.nih.gov/, citation database of peer-reviewed journals. I used the MeSH (Medical Subject Headings) browser,http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=mesh, to build the following search strategy: "Human Growth Hormone"[MeSH] AND "Leg"[MeSH] AND "Exercise"[MeSH] You can perform this search on the same or similar words in free text, too. Just leave off the [MeSH] markers, and you'll probably get slightly different results. Here are four articles. 1: Bosco C, Iacovelli M, Tsarpela O, Cardinale M, Bonifazi M, Tihanyi J, Viru M, De Lorenzo A, Viru A. Hormonal responses to whole-body vibration in men. Eur J Appl Physiol. 2000 Apr;81(6):449-54. PMID: 10774867 [PubMed - indexed for MEDLINE] 2: Takarada Y, Nakamura Y, Aruga S, Onda T, Miyazaki S, Ishii N. Rapid increase in plasma growth hormone after low-intensity resistance exercise with vascular occlusion. J Appl Physiol. 2000 Jan;88(1):61-5. PMID: 10642363 [PubMed - indexed for MEDLINE] 3: Viru M, Jansson E, Viru A, Sundberg CJ. Effect of restricted blood flow on exercise-induced hormone changes in healthy men. Eur J Appl Physiol Occup Physiol. 1998 May;77(6):517-22. PMID: 9650736 [PubMed - indexed for MEDLINE] 4: Hakkinen K, Pakarinen A, Newton RU, Kraemer WJ. Acute hormone responses to heavy resistance lower and upper extremity exercise in young versus old men. Eur J Appl Physiol Occup Physiol. 1998 Mar;77(4):312-9. PMID: 9562359 [PubMed - indexed for MEDLINE] I also located the following articles, using the following search string, "growth hormone" physiology exercise, limiting results to "review" articles and where the search terms occur in the title/abstract. 1: Jenkins PJ. Growth hormone and exercise: physiology, use and abuse. Growth Horm IGF Res. 2001 Jun;11 Suppl A:S71-7. Review. PMID: 11527092 [PubMed - indexed for MEDLINE] 2: Hartman ML, Veldhuis JD, Thorner MO. Normal control of growth hormone secretion. Horm Res. 1993;40(1-3):37-47. Review. PMID: 8300049 [PubMed - indexed for MEDLINE] 3: Bar-Or O. Clinical implications of pediatric exercise physiology. Ann Clin Res. 1982;14 Suppl 34:97-106. Review. PMID: 6756277 [PubMed - indexed for MEDLINE] I suggest that you utilize the databases at your own or a nearby college or university to obtain the full text articles noted in journals from the PubMed searches. Be sure to talk with a librarian there if you need help accessing these. They may be able to order them through Interlibrary Loan for you if they are not available in their full text databases. Googling http://www.google.com) on terms, such as "growth hormone" physiology, and limiting results to sites that are more likely to be authoritative, such as .edu or .gov also returned many results. "Growth Hormone." This is a free encyclopedia entry. http://encyclopedia.thefreedictionary.com/growth%20hormone "Exercise-dependent growth hormone release is linked to markers of heightened central adrenergic outflow" by Arthur Weltman, Cathy J. Pritzlaff, Laurie Wideman, Judy Y. Weltman, Jeffery L. Blumer, Robert D. Abbott, Mark L. Hartman, and Johannes D. Veldhuis. J Appl Physiol 89: 629-635, 2000. http://jap.physiology.org/cgi/content/full/89/2/629 Hormones and Resistance Exercise by Derek Marks, M.S. and Len Kravitz, Ph.D. http://www.unm.edu/~lkravitz/Article%20folder/growthhormone.html Browse MedlinePlus's,http://medlineplus.gov/, index of resources for the health consumer on the topic, "Human Growth Hormone," and follow the links that interest you. Here are a few. "Human Growth Hormone"http://search.nlm.nih.gov/medlineplus/query?DISAMBIGUATION=true&FUNCTION=search&SERVER2=server2&SERVER1=server1&PARAMETER=human+growth+hormone&x=70&y=9 Adult Growth Hormone (GH) Deficiency http://www.pituitary.org/disorders/gh_deficiency.aspx The Endocrine system (Overview) from the Hormone Foundation. http://www.hormone.org/endo101/index.html Endocrine Glands & Their Hormones http://training.seer.cancer.gov/module_anatomy/unit6_3_endo_glnds.html "Growth Hormone" from WebMD http://my.webmd.com/search/search_results?query=human+growth+hormone&filter=mywebmd_all_filter American Association of Clinical Endocrinologists. Click on the link on the left side of the page for Services and then Links. http://www.aace.com/index.php Thanks for an interesting question. Good luck with your research. Sincerely, Joyce